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BioProfiler

Microorganism Identification based on MALDI-TOF-Mass Spectrometry

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Biological hazardous threats

Worldwide there is an evident danger for the use of biological hazardous agents as weapons of mass destruction. The terrifying fact about bio hazards is the possibility of its fast and uncontrollable spread into the environment.
Therefore the reliable and fast identification of microorganisms is a challenging task in mobile or stationary labs.

Identification of unknown microorganisms

BioProfiler- microorganism identification based on MALDI-TOF Mass Spectrometry is a software tool that allows the reliable identification of unknown microorganisms from their protein fingerprint in the MALDI-TOF mass spectrum by comparing their individual peak lists to the available database. Based on a flexible database approach the data obtained by MALDI-TOF mass spectrometry from cultivated bacterial colonies can be easily analysed.

Key features

  • Ready-to-use databases are available including a database for bacteria based Biological Warfare Agents ( BWA)
  • Adjustable to new threats by creating your own database
  • Training mode to extend existing databases or those provided by Bruker Daltonics
  • User and application training
  • Scoring factors allowing the interpretation of identification results

Fields of Application

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Easy operation

The BioProfiler software offers two levels of operation. Easy and fast identification incorporates loading the library and starting the pattern matching based evaluation procedure. It incorporated the measurement of several substances in one go.
Even different microbial strains of the same species can be distinguished with the described method. The advanced level enables the laboratory professional to create an individual data base out of their own collected available samples in order to address new threats.

Technical Specification

System requirements:

Works on Windows XP based computers with at least 2 GHz, 512 MB RAM and 256 MB free desk capacity

Samples:

Bacteria (gram+/gram-), yeasts, fungi, spores

Instrumentation:

Bruker flex series mass spectrometers with instrument control software

For research use only. Not for use in diagnostic purposes.

 
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