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Bruker Daltonics
Bruker

ProteomeQuant – A Highly efficient Solution for Biomarker Discovery and label-free Identification of Regulated Proteins in Biological Systems

Type: Application

Technical Note

Expression Proteomics, Clinical Proteomics

Number: Technology

TN-27

OTOF, MALDI-TOF

Year Products

2008

  Author
 

W. Jabs, L. C. Main, M. Behrens, C. Bäßmann, Bruker Daltonik GmbH Bremen

  Reference
 

Technical Note # TN-27

 

Abstract

 

A label-free solution for quantitative proteomics is presented which is based on a highly stable LC-MS/MS system offering high mass resolution, accuracy and sensitivity. Combining this system with powerful bioinformatics analysis and data-warehousing software, allows for comprehensive high-throughput quantitative studies. This is demonstrated using a human lung carcinoma cell line as model system.

 

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