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Altered Glycosylation Pattern of Total Serum IgG in Patients with Rheumatoid Arthritis analyzed by MALDI-TOF MS

Type: Application

Poster

Expression Proteomics
Number: Technology

TPZ 610

MALDI-TOF
Year Products

2009

  Author
 

Katrin Sparbier1, Hassan Dihazi3, Sabine Blaschke3, Gerhard-Anton Mueller3, Thomas Flad2 and Markus Kostrzewa1, Ray Sanchez4
  Reference
 

 

Abstract
 

  • A simple, quick and reliable method based on MALDI-TOF MS for the analysis of N-glycans has been developed.

  • This method allows for the relative quantitation of different glycan structures.

  • The relative extent of galactosylated bi-antennary complex glycans of IgGs is decreased in patients with RA.
 

Related Products
 

ASMS 2009
 

Download

 

ASMS_2009_Sparbier_et_al_Glycan_profile_01.pdf
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