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Bruker Daltonics
Bruker

High Confidence in Protein Identification using ppb mass accuracy by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Type: Application

Poster

Expression Proteomics

Number: Technology

ThPG 189

FTMS

Year Products

2009

  Author
 

Matthias Witt and Jens Fuchser

  Reference
 

 

Abstract

 

• Confidence level of correct protein
   identification can greatly be
   improved with mass accuracies of
   precursor and fragment masses in
   the ppb range.

• 134 proteins could be identified in
   E.coli digest by MASCOT database
   search using a mass tolerance of
   1ppm with a decoy false discovery
   rate of only 1.1%.

 

Related Products

 

ASMS 2009

 

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