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LC-NALDI: Using Matrix-Free Nanostructured Targets for Peptide Fractionation and Analysis
| Type: | Application |
Poster |
Expression Proteomics |
| Number: | Technology |
MPZ 572 |
MALDI-TOF |
| Year | Products |
2009 |
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| Author | |
Sergei Dikler, Paul Kowalski |
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| Reference | |
Abstract |
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•NALDI targets are suitable for analysis of peptides in broad mass range using high throughput matrix-free LC-LDI workflow. •NALDI targets show particularly high sensitivity for peptides below 1700 Da. •Fragmentation patterns of peptides in MS/MS spectra acquired from NALDI targets are identical to fragmentation patterns from conventional MALDI preparations. •Analyses of peptides below 900 Da using NALDI targets have advantage of fewer background signals in comparison to conventional MALDI preparation. |
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