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Bruker Daltonics
Bruker

MALDI Tissue Imaging of Drugs with the ultraflex MALDI TOF/TOF

Type: Application

Application Note

Number: Technology

MT-87

MALDI-TOF
Year Products

2007

ultraflex II, flexImaging, MALDI Molecular Imager
  Author
 

Jane-Marie Kowalski1, Paul Kowalski1, Armin Holle2, Sören-Oliver Deininger2, Sheerin Khatib-Shahidi3 and Richard Caprioli3
[1] Bruker Daltonics, Inc., Billerica, MA; [2] Bruker Daltonik GmbH, Bremen, Germany; [3] Vanderbilt University, Nashville, TN.
  Reference
 

Bruker Daltonics Application Note MT-87
 

Abstract
 

MALDI-TOF/TOF analysis can be used to detect

and image drug molecules and their metabolites

in tissue.

In addition to other Mass Spectrometry (MS) methodologies used for determining the localization of small molecules in tissue, MALDI-TOF/TOF can also be used to detect drugs and their metabolites in tissue without the burden of matrix interference.
 

Related Products
 

flexImaging
Small Molecule Tissue Imaging
ultrafleXtreme series
 

Download

 

mt-87-small-molecules-imaging.pdf
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