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Sequence Characterization of monoclonal Antibodies based on a combined LC-MS/MS Approach powered by sophisticated Bioinformatics

Type: Application

Application Note

Expression Proteomics

Number: Technology

PWA-453

MALDI-TOF, Ion Trap, FTMS, OTOF, UHR-TOF

Year Products

2009

  Author
 

Elisa Basso1, Arndt Asperger2, Matthias Witt2, Ulrike Schweiger-Hufnagel2, Romano Hebeler2, Andrea Schneider2, Peter Hufnagel2, Pierre-Olivier Schmit3 and Marcus Macht2

  Reference
 

Poster IMSC 2009

 

Abstract

 

Sequence characterization in a highly complex workflow:

  • Integrated presentation of all results (gel, in-solution digest, MS instruments, peptide matching parameters)
  • Interactive SequenceViewer for easy navigation in results
    An excellent sequence coverage for the recombinant antibody resulted: 100 %, and 99 %

 

Related Products

 

IMSC 2009

 

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