Ibis T5000 Biosensor
Nucleic acid based detection and characterization of microorganisms
Rapid and reliable identification of microorganisms associated with human infection diseases is a challenging task in health care units as well as in other surveillance environments, considering alone the fact of more than 1400 human pathogenic organisms yet known.
The Ibis T5000 Biosensor is a new integrated technology – developed from our cooperation partner Ibis Biosciences in Carlsbad, California – and manufactured and distributed by Bruker Biosciences. It offers robust, fast, and automated identification of microorganisms, combining established Polymerase Chain Reaction (PCR) methods with state of the art electrospray Time of Flight Mass Spectrometry.
Applications
- High throughput strain typing and drug resistance profiling of hospital acquired infection dieseases.
- Identification of unknown (often uncultivable) microbes associated with infection diseases.
- Methicillin-resistant Staph. Aureus (MRSA) genotyping and antibiotic resistance characterization.
- High Throughput pan-influenza surveillance (human and avian)
Unique features
- Broad and rapid analysis – analyze a sample for thousands of pathogens in a few hours.
- Direct specimen analysis – analyze directly from a vast array of sample without first culturing.
- Universal platform – identify, characterize and quantify virtually any clinical relevant viral, bacterial, or fungal component.
- High Throughput – dependent on assay up to hundreds of samples can be analyzed in a 24 hour period.
- Robust system – highly validated assays are ready to go.
- Simple workflow T5000 automation and Ibis assay kits makes the T5000 system easy to use.
- Extensive, expandable organism database.
- Analysis of new emerging species.
How does the Ibis T5000 Biosensor work?
Although the focus is on hospital acquired infections and influenza surveillance initially, the method generally has the potential to be extended to broad groups of viruses, fungi and pathogenic protozoa. Due to a high degree of automation and software control, the system can be operated by a properly trained technician with no training in mass spectrometry, signal processing or molecular biology.
For research use only. Not for use for diagnostic purposes.
In cooperation with Ibis Biosciences, a Subsidiary of Isis Pharmaceuticals Inc. Carlsbad, CA, USA
