Clinical Proteomics

Mass spectrometry continues to contribute its ability as a superior tool for protein expression profiling and analysis of biomarker patterns from bodily fluids and tissues. These scientific applications are addressing areas such as predictive medicine, toxicology and in the very near future, diagnostics.
Bruker Daltonics' CLINPROT suite ideally satisfies scientists' needs in advanced biomarker related pre-clinical research.

Watch the IMSC 2006 presentation "Clinical Biomarker Discovery Integrated with MALDI Molecular Imaging" in a 17 minute video.

Analytical challenge	Methods	Our Solution	Further Reading
Biomarker Detection, Identification and Validation	Sample Prefractionation	Magnetic Bead Based Sample Preparation	TN 013, MT-72
	MALDI-TOF Based Profiling	microflex microflex LT	Brochure CLINPROT micro, Brochure CLINPROT
	MALDI-TOF/TOF MS based Biomarker ID	microflex microflex LT
	Biomarker visualization and evaluation		BT38 06/05
	Biomarker Identification	autoflex ultraflex ClinProTools BioTools
MALDI Imaging	ImagePrep sample preparation smartbeam	MALDI Molecular Imager	LPI 06/05, TN 012, BPI 01/06, TN 018
Microorganism strain-specific fingerprinting	Direct MALDI-TOF based Microorganism profiling, dedicated software evaluation	MALDI BioTyper microflex microflex LT autoflex	MT-80
Identification of urinary nucleosides	Structural assignment of known and unknown nucleosides from urine samples	micrOTOF micrOTOF-Q SigmaFit True Isotopic Pattern	LCGC 12/05