Compass

Compass™ is Bruker Daltonic´s new unified software environment for intuitive mass spectrometric instrument control and data processing, as well as for powerful chemoinformatics and bioinformatics analysis software.

The Common Interface

Compass is designed to offer a unified look and feel for instrument control and processing. Compass provides tools to aid both novice and expert users to acquire and process datasets and interpret results efficiently on all Bruker Daltonics life-science systems. Within the Compass environment, specific modules are selected, depending on the instrument and applications needs.

Compliance with FDA and EU regulations

All Compass data acquisition and processing modules will provide the necessary functions needed to work in compliance with FDA and EU regulations (21CFR, Part 11/Annex 11) requirements.

A Modular System

Advanced Compass data interpretation uses additional chemo-/bioinformatics modules, depending on the applications requirements. Examples include QuantAnalysis, Biotools for protein sequence confirmation, RapiDeNovo for sequencing of peptides, MetaboliteTools for advanced comparison of different LC/MS datasets to pinpoint the presence of low levels of metabolites and predict the structures of the metabolites, and LibrarySearch for comparison of MS/MS spectra against reference spectra.

The Most Comprehensive Instruments Support

The latest version of Bruker Daltonics COMPASS software for LC/MS has been enhanced to support the Waters® ACQUITY UPLC™ system. The new plugin-based interface allows users to operate the esquire/HCT ESI-Ion Trap and the micrOTOF/micrOTOF-Q mass spectrometers in combination with Waters® ACQUITY UPLC™ as one integrated LC/MS system.

Support of all advanced instruments such as

  • API Ion Traps
  • FTMS systems
  • orthogonal API-TOF
  • MALDI-TOF
  • Bruker BioSpin AVANCE™ NMR spectrometers in LC-SPE-NMR/MS setup

The Compass software supports a wide range of LC instruments through the HyStar™ interface, e.g.:

  • Agilent (most 1100/1200 series instruments)
  • Dionex (UltiMate™ and UltiMate 3000™)
  • Hitachi (LaChrom Elite® HPLC System)
  • Waters (ACQUITY UPLC™, Alliance 2695, 2795, etc.)

Features

with

  • simple graphical user interface (GUI)
  • customized spectral and chromatographic displays
  • tabulated windows for tuning, calibration and setup of specific parameters (e.g. MS/MS conditions)
  • Elemental composition calculation
  • isotopic pattern comparisons
  • internal and external recalibration
  • VBScripting for automated or complex processing
  • ReportDesigner to create customized reports in different formats.

Compass data interpretation, such as

  • QuantAnalysis
  • Biotools for protein sequence confirmation
  • RapiDeNovo for sequencing of peptides
  • MetaboliteTools for advanced comparison of different LC/MS datasets
  • LibrarySearch for comparison of MS/MS spectra against reference spectra
  • Proteinscape for Proteomic Project Management
  • GenoTools ...
  • ClinProTools …

Compliance with FDA 21CFR, Part 11 and EU regulations by Compass Security Pack™

  • electronic signatures
  • audit trailing
  • user management
  • result history
  • system protection during breaks
click for larger image
click for larger image