BIOForum Europe publishes a -Product Focus Spectrometer- article, featuring the Bruker Daltonics HCTultra ion trap

November 2005 - BIOForum Europe published a "Product Focus Spectrometer" article entitled "Mass Spectrometric Large-Scale Proteome Analysis", describing research done with the Bruker Daltonics HCTultra ion trap. "Mass spectrometers have become essential for the analysis of complex proteomes. Ion trap mass analysers are advantageous in proteomics applications due to their high duty cycle for a combined MS and MS/MS analysis, allowing successful protein identification by peptide fragmentation analysis. However, the detection of low-abundant proteins is limited in highly complex samples by dynamic range and acquisition speed of the instrument. Thus proteins of particular interest may be lost...The new HCTultra ion trap dramatically increases the number of identified proteins compared to the renowned HCTplus in any large-scale proteomics application. Outstanding detection rates of low-abundant peptides and high sequence coverage of the entity of proteins are a result of the renowned mass accuracy as well as remarkable improvements in speed and sensitivity in the HCTultra."