APPI II: Access to less or non-polar compounds
Atmospheric pressure photo ionization (APPI) is used for less polar or non-polar molecules that can not be ionized in either ESI or APCI. APPI II by Bruker Daltonics is the only APPI source with DirectProbe option for direct analysis of solid samples.
APPI delivers a wide dynamic range and low chemical noise. With an operational flow range of 2µl/min – 1500µL/min it is compatible with cap- to analytical chromatography.
The new Bruker APPI II source is off course compatible to Bruker’s unique DirectProbe option DIP and all current MS systems of Bruker Daltonics. The direct injection probe is a novel smart solid sample introduction technique allowing a rapid analysis of solids. Sample preparation is as simple as dipping a disposable glass capillary into the solid sample.
The DirectProbe enables analysis of a wide range of substances – e.g. crude oil.

- The example shows the results of a quick manual QC and Comparison of petroleum cuts with an amaZon SL. The three candidates gas oil vacuum gas oil and vacuum residue are clearly distinguishable without any sample preparation and no memory-effect due to single use sample tubes.
Related products
Further reading
TN38: Fast and reliable Reaction Yield and Compound Purity Assessment in Synthesis Quality Control


